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NASA astronauts Jessica Meir and Jack Hathaway, European Space Agency astronaut Sophie Adenot, and Russian cosmonaut Andrey Fedyaev were originally going to overlap in space with the outgoing crew, a mission known as Crew-11. But that group had to return to Earth early because of a medical issue. (NASA did not disclose the identity of the affected astronaut or the nature of the incident for privacy reasons.)

The Crew-11 astronauts departed on Jan. 14, leaving a sole NASA astronaut, Chris Williams, onboard the International Space Station, along with two Russian cosmonauts.

The four new arrivals, together known as Crew-12, will bring the space station up to its standard occupancy of seven people. Their SpaceX capsule is expected to dock Saturday around 3:15 p.m. ET.

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